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  5. IL-17 Secretion Assay – Cell Enrichment and Detection Kit (PE), human

IL-17 Secretion Assay – Cell Enrichment and Detection Kit (PE), human

MB130-094-542

The IL-17 Secretion Assay – Cell Enrichment and Detection Kit was developed for the sensitive detection and enrichment of viable human IL-17–secreting leukocytes from PBMCs. The used Anti-PE MicroBeads UltraPure enhances sensitivity and minimizes background of debris and dead cells. For research use only. Size: for 50 tests

Brand: Miltenyi Biotec

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Background information
Interleukin 17 (IL-17) is produced by CD4+ T helper cells, a T cell subset termed Th17, which also secrete IL-17F and IL-22 and express the NK cell marker CD161. IL-17 secretion has also been described for other cell types, such as CD8+ memory T cells.
Th17 cells are involved in the recruitment of neutrophils to control early stages of infections by a number of pathogens, such as extracellular bacteria and fungi. IL-17 and Th17 cells play an important role in immune-mediated inflammatory diseases, such as rheumatoid arthritis, psoriasis, multiple sclerosis, asthma, and inflammatory bowel disease.
Columns
MS, LS, or autoMACS® Columns.