Cell Separation 

Background information
Epidermal LCs are the principal dendritic cell population in the epidermis and play a pivotal role in the initiation and maintenance of primary immune responses in the skin. Immature LCs are highly specialized in antigen uptake. In vivo LCs exposed to pathogens migrate from the skin to the draining lymph nodes, where they elicit antigen-specific T cell responses.
Applications
Positive selection or depletion of mouse epidermal Langerhans cells from single-cell suspension prepared from epidermis using the Epidermis Dissociation Kit, mouse.
Columns
For positive selection: MS, LS, or autoMACS® Columns. For depletion: LD or autoMACS Columns.