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CD371 (CLEC12A)-PE, mouse

MB130-109-341

Clone REA594 recognizes the mouse CD371 (CLEC12A) antigen, a 30 kDa type II transmembrane protein with extracellular C-type lectin domains. CD371 (CLEC12A) is a member of the C-type lectin/C-type lectin–like domain (CTL/CTLD) superfamily which have a common protein fold and plays a role in cell adhesion, cell-cell signaling, glycoprotein turnover, inflammation, and immune response.CD371 expression is primarily found on granulocytes and monocytes but also on CD8+ dendritic cells (DCs), plasmacytoid DCs, granulocytes, and B cells. It associates with the signaling phosphatases SHP-1 and SHP-2, but not with SHIP and is a negative regulator of granulocyte and monocyte function. For research use only. Size: 9 µg in 300 µL

Brand: Miltenyi Biotec

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MB130-109-341 CD371 (CLEC12A)-PE, mouse CD371 (CLEC12A)-PE, mouse Login for price  

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Additional information: Clone REA594 displays negligible binding to Fc receptors.
Alternative names
CLL-1, MICL, DCAL-2

Antigen: CD371 (CLEC12A)
Clone: REA594
Isotype: recombinant human IgG1
Isotype control: REA Control antibodies
Alternative names of antigen: CLL-1, MICL, DCAL-2
Entrez Gene ID: 232413
Molecular mass of antigen [kDa]: 31
Distribution of antigen: granulocytes, monocytes, dendritic cells, B cells
Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
Storage: Store protected from light at 2–8 °C. Do not freeze.
Available conjugates: VioBright FITC, PE, APC, Biotin