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CD2-Biotin - functional grade, human

MB130-093-376

The CD2 antibody recognizes the human CD2 antigen, a 50 kDa single-chain transmembrane glycoprotein also known as LFA-2 or receptor for sheep erythrocytes. It reacts with 80–90% of peripheral blood lymphocytes and more than 95% of thymocytes. The antibody recognizes all T cells and a subset of natural killer (NK) cells. Activation and proliferation of T cells can be induced by interaction of the T cell receptor with peptide-MHC complexes expressed on the surface of antigen-presenting cells (APCs). The T cell receives a signal transduced through the CD3 complex. Cytokines or other costimulatory signals are required in addition. Activated T cells can be used for any downstream processes, such as cytokine analysis or immunoprecipitation. For research use only. Size: 100 µg in 1 mL

Brand: Miltenyi Biotec

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Applications
The CD2-Biotin – functional grade antibody is suited for functional assays, for example, activation and expansion of T cells together with CD3-Biotin – functional grade antibody, CD28-Biotin – functional grade antibody, and Anti-Biotin MACSiBead™ Particles, cell culture grade.
Alternative names
LFA-2, SRBC-R, T11, SRBC

Antigen: CD2
Clone: LT2
Isotype: mouse IgG2b
Alternative names of antigen: LFA-2, SRBC-R, T11, SRBC
Entrez Gene ID: 914
Molecular mass of antigen [kDa]: 37
Cross-reactivity: rhesus monkey ( Macaca mulatta ), cynomolgus monkey ( Macaca fascicularis ), chimpanzee ( Pan troglodytes ), squirrel monkey ( Saimiri sciureus )
Distribution of antigen: B cells, lymphocytes, macrophages, mast cells, NK cells, T cells, thymocytes
Endotoxin level: Endotoxin levels have been tested and do not exceed 0.01 ng/µg of protein.
Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
Storage: Store protected from light at 2–8 °C. Do not freeze.