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  5. Antibodies
  6. Mouse Immunology
  7. APC/Fireª 750 anti-mouse CD117 (c-kit)

APC/Fireª 750 anti-mouse CD117 (c-kit)

CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.

Brand: Biolegend

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Product CodeProduct Product Description Price (Excl gst) Qty Add
BIO105838 APC/Fireª 750 anti-mouse CD117 (c-kit) 100 µg APC/Fireª 750 anti-mouse CD117 (c-kit) 100 µg Login for price  
BIO105837 APC/Fireª 750 anti-mouse CD117 (c-kit) 25 µg APC/Fireª 750 anti-mouse CD117 (c-kit) 25 µg Login for price  

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Isotype Control APC/Fire™ 750 Rat IgG2b, κ Isotype Ctrl

Reactivity Mouse

Immunogen Mouse bone marrow mast cells

Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation The antibody was purified by affinity chromatography and conjugated with APC/Fire™ 750 under optimal conditions. The solution is free of unconjugated APC/Fire™ 750 and unconjugated antibody.

Concentration 0.2 mg/ml Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application FC - Quality tested

Recommended Usage Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

* APC/Fire™ 750 has a maximum excitation of 650 nm and a maximum emission of 787 nm.

Size 25 or 100 µg