Enjoy FREE SHIPPING on all FreeStyle Libre 2 purchases until 31 May 2024. Simply enter promo code FREESHIP at checkout and click ‘SUBMIT CODE’ to apply!
Pharmac proposes to commence FreeStyle Libre 2 subsidy for people living with type 1 diabetes! Read more
Menu
X
If you know the product code enter it here
Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 (B7-H1) and PD-L2 (B7-DC) are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
Brand: Biolegend
Go to checkout
