Cell biology 

In less than an hour, it is possible to

• separate pluripotent mouse ES or iPS cells from heterogeneous cultures, e.g. to eliminate feeder cells,
• enrich reprogrammed mouse iPS cells,
• deplete unwanted pluripotent cells from ES or iPS cell-derived differentiation cultures,
• deplete human ES or iPS cells that have undergone spontaneous differentiation.

Background information
In the murine system, SSEA-1 is one of the key embryonic stem (ES) cell markers associated with the state of pluripotency. It is known to be expressed on undifferentiated murine ES and induced pluripotent stem (iPS) cells. In contrast, SSEA-1 is not expressed on undifferentiated human ES cells but becomes upregulated during spontaneous differentiation.
Columns
For positive selection: MS, LS, XS, or autoMACS® Columns. For depletion: LD, D, or autoMACS Columns.