An important update is available for FreeStyle LibreLinkØ. Check here for more information.

 

X
Menu
Cart
X

Search Website

QUICK ORDER PRODUCTS

If you know the product code enter it here  

  1. Home
  2. Laboratory
  3. Molecular and Microbiology Reagents
  4. Molecular
  5. Gene Function
  6. RetroNectin reagent

RetroNectin reagent

TKT100B

Research using hematopoietic cells and other suspension cells has been limited in part by low efficiency of gene transfer (transduction and transfection) into these cell types. RetroNectin reagent promotes colocalization of lentivirus or retrovirus with target cells to dramatically enhance transduction efficiency. As a consequence, RetroNectin reagent is now the gold standard transduction enhancer for retroviral/lentiviral gene transfer to hematopoietic cells and holds great promise in clinical application, having been used for over 40 clinical trials.

Brand: Takara

Learn more

Select your options below
Enquire about this product
Product CodeProduct Product Description Price (Excl gst) Qty Add
TKT100B RetroNectin® Recombinant Human Fibronectin Fragment, 2.5 mg RetroNectin® Recombinant Human Fibronectin Fragment, 2.5 mg Login for price  

Go to checkout

X

Stock Request

Submit your details.
You are enquiring about RetroNectin reagent

Pricing Request Starts Here

Submit your details to receive a quote.
You are enquiring about RetroNectin reagent

RetroNectin reagent is a 63-kD fragment of recombinant human fibronectin fragment (also referred to as rFN-CH-296) that enhances the efficiency of lentiviral- and retroviral-mediated gene transduction. This is particularly important for hematopoietic cells and other hard-to-transfect cell types. When coated on the surface of containers such as culture dishes, petri dishes, flasks or bags, RetroNectin significantly enhances virus-mediated gene transduction into mammalian cells. This enhanced transduction is thought to result from the colocalization of virus particles and target cells on the molecules of RetroNectin. Viral particles bind RetroNectin via interaction with heparin-binding domain II, and target cells bind mainly through the interaction of the cell surface integrin receptor VLA-4 with the fibronectin CS1 site.