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  6. Neutrophil Isolation Kit, mouse

Neutrophil Isolation Kit, mouse

MB130-097-658

The Neutrophil Isolation Kit has been developed for the isolation of untouched neutrophils from mouse bone marrow or blood cell suspensions. For research use only. Size: for 1×10^9 total cells

Brand: Miltenyi Biotec

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Background information
Neutrophils are essential for host defense against invading pathogens. They are phagocytic polymorphonuclear cells, which engulf and degrade microorganisms using a wide range of toxic agents including reactive oxygen species, antimicrobial peptides, and proteases. Besides, neutrophils can produce anti-inflammatory molecules and factors that promote the resolution of inflammation.
Detailed separation procedure
Non-neutrophils are incubated with a cocktail of biotinylated antibodies and Anti-Biotin MicroBeads for depletion.
Downstream applications
Functional studies on neutrophils.
Studies on neutrophil activation, differentiation, cytokine secretion etc.
Studies on signal transduction in neutrophils.
Columns
LS Columns for neutrophil isolation from bone marrow, MS Columns for neutrophil isolation from peripheral blood, or autoMACS® Columns.