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Anti-EOMES-PE, mouse

Clone REA116 recognizes EOMES, also known as T-box brain protein 2 (TBr2) or eomesodermin. EOMES is a 72–74 kDa T-box transcription factor and plays a crucial role in development including trophoblast differentiation, gastrulation, brain development, and cell-mediated immunity in adults. EOMES lacking embryos are arrested at the blastocyst stage due to differentiation defects of the trophoectoderm. As a regulator of cell mediated immunity, expression of EOMES is shown to be increased in effector CD8+ T cells, in response to infection. Further, EOMES including its paralogue T-bet are suggested to be involved in NK cell maturation. For research use only.

Brand: Miltenyi Biotec

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Product CodeProduct Product Description Price (Excl gst) Qty Add
MB130-102-419 Anti-EOMES-PE, mouse, Size: 30 µg in 1 mL Anti-EOMES-PE, mouse, Size: 30 µg in 1 mL Login for price  
MB130-102-916 Anti-EOMES-PE, mouse, Size: 9 µg in 300 µL Anti-EOMES-PE, mouse, Size: 9 µg in 300 µL Login for price  

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Additional information: Clone REA116 displays negligible binding to Fc receptors.

Alternative names
TBR-2

Technical specifications
Antigen: EOMES
Clone: REA116
Isotype: recombinant human IgG1
Isotype control: REA Control antibodies
Alternative names of antigen: TBR-2
Entrez Gene ID: 13813
Molecular mass of antigen [kDa]: 75
Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
Storage: Store protected from light at 2–8 °C. Do not freeze.
Available conjugates: PE, APC

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