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  5. Single-cell library prep for SNV and CNV detection

Single-cell library prep for SNV and CNV detection

The SMARTer PicoPLEX Gold Single Cell DNA-Seq Kit (PicoPLEX Gold) is designed to generate high-quality DNA libraries from single cells for sequencing on Illumina platforms. The kit is based on our patented PicoPLEX technology and is optimized for the reproducible detection of copy number variants (CNVs), single nucleotide variants (SNVs), indels, and small structural variants. The PicoPLEX Gold kit outperforms the leading Multiple Displacement Amplification (MDA) technology for SNV detection.

Brand: Takara

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Overview

  • Highly reproducible and accurate CNV, SNV, and aneuploidy detection
  • Outperforms the leading MDA technology for SNV and CNV detection
  • Streamlined three-hour workflow with less than 30 minutes of hands-on time
  • Highly uniform coverage with low allele drop-in and drop-out rate

Applications

Library preparation for the following cell types:

  • Cancer research: circulating tumor cells, cells, or DNA from laser capture microdissection (LCM), and cells from fine needle aspirate (FNA)
  • Reproductive health research: embryonic cells and circulating fetal cells
  • Developmental biology: embryonic cells, stem cells, and rare cells
  • Metagenomics and microbiology: microbial cells, microbiome and environmental samples