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SMARTer ThruPLEX Plasma-Seq Kit—cell-free DNA library preparation for Illumina NGS platforms

SMARTer ThruPLEX Plasma-Seq kits are powered by SMARTer ThruPLEX chemistry to generate high-performance NGS libraries from cell-free DNA isolated from plasma. The chemistry has been specifically optimized for cell-free DNA to maximize library complexity and to preserve the GC representation of the input sample. Libraries can be used for CNV analysis, whole-genome sequencing applications, or enrichment using your custom panels or leading target enrichment platforms, such as Agilent SureSelect and Roche NimbleGen SeqCap EZ.

Brand: Takara

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Features

  • Designed for cell-free DNA—newly formulated repair and ligation reagents with optimized protocols
  • High-performance NGS libraries—high library diversity with broad and reproducible GC coverage
  • Variable sample input—<1 ng to 30 ng of cell-free DNA
  • Fast and simple workflow—three steps in a single tube or well in two hours, with no purification or sample transfer steps (tubes and plates sold separately)
  • Research applications—construct libraries from samples where results require high sensitivity, including liquid biopsies, ctDNA, and targeted sequencing
  • Automation friendly—compatible with the Beckman FXP Workstation